The response

■ President Obama said in a statement: “The people of the United Kingdom have spoken, and we appreciate their decision.” He pledged that the U.ok. and the E.U. could stay “imperative partners of the usa” and that Britain’s “special dating” with the united states would bear.

■ Hillary Clinton: “We appreciate the choice the people of the UK have made. Our first challenge needs to be to ensure that the economic uncertainty created by using these occasions does now not harm operating families here in the usa.”

■ Donald J. Trump: “I said this become going to occur, and i think that it’s a first-rate issue.”

The British people “have declared their independence from the ecu Union, and have voted to reassert manipulate over their very own politics, borders and economic system,” Mr. Trump said. “A Trump administration pledges to bolster our ties with a free and unbiased Britain.”

  ■ Chancellor Angela Merkel of Germany expressed unhappiness with the vote and referred to as for ecu unity. “Our goal have to be to create a future courting among wonderful Britain and the eu Union that is near and companion-like.”

■ Moscow maintained its stance that the British referendum become of little direct challenge. President Vladimir V. Putin stated, “this may truely have effects for Britain, for Europe and for us. The outcomes may be worldwide, they're inevitable; they may be both high quality and bad.”

■ The French some distance-proper cheered the vote, with Marine Le Pen, the chief of the countrywide front celebration, vowing to push for the same referendum there.